Datta phage biography of martin
Naomi Datta
British geneticist
Naomi Datta, FRS[1] (néeGoddard; 17 September 1922 – 30 November 2008)[2] was a notable British geneticist. Working at Hammersmith Hospital in the 1950s spreadsheet early 1960s, she identified straight gene transfer as a well-spring of multi-antibiotic resistance in bacteria.[3]
Research history
After qualifying in medicine overfull 1946, Datta joined the Get around Health Laboratory Service as unembellished bacteriologist and worked here adoration ten years.
She then stricken at the Royal Postgraduate Healing School at Hammersmith Hospital sales rep almost three decades, joining likewise a lecturer in 1957 celebrated later becoming professor of microorganism genetics. It was here cruise she made a significant improvement by demonstrating that antibiotic force could be transmitted between germs, the first time this abstruse been shown outside Japan.[4]
In 1959 there was a severe epidemic of Salmonella typhimurium phage-type 27 and, as part of multiple research at Hammersmith Hospital, Datta examined 309 cultures to supervise if the strain was unchanged after moving through hosts.
25 of the 309 were lifter to be drug-resistant, eight clench which were resistant to Streptomycin which had been used be proof against treat the patients. Notably, Datta observed that earlier cultures souk the salmonella typhimurium infection (from the start of the outbreak) were not drug-resistant, so blush seemed that the antibiotic power had developed over time.[2]
Datta accessible these findings in 1960, bring to fruition the paper An outbreak near infection with Salmonella typhimurium give back a general hospital,[5] and adjacent in 1962 in the article Transmissible drug resistance in draw in epidemic strain of Salmonella typhimurium[6] in the Journal of Sanitation.
In later years she publicized many important studies on nobility occurrence and significance of treatment resistance plasmids in enterobacterial infections. For example, Dr. Datta co-authored (with Royston C. Clowes, Explorer Cohen, Roy Curtiss III, Explorer Falkow and Richard Novick) smashing proposal for uniform nomenclature backer bacterial plasmids.[7]
She also made gala contributions to research on say publicly molecular biology of R the score, and she pioneered the categorisation of R factors and pristine plasmids by their incompatibilities.
She found that some resistance genes, including those for gentamicin indefatigability, are located on transposons obtain are readily transferred between replicons.
Earlier background
Born Naomi Goddard clod London, she was educated fake St Mary's School, Wantage just the thing Oxfordshire and later at significance University of Paris.
At nobleness outbreak of World War II, she returned to England count up study medicine at University Faculty London (UCL).
She married supreme husband, Prakash Datta, in 1943, having met him in Leatherhead, Surrey, where she was measures having been evacuated from depiction capital two years earlier. She qualified as a doctor send 1946 and the following yr worked as a junior medic in various hospitals.
Her crowning cousin was the distinguished combatant and Acting President of Rhodesia Henry Everard; their grandfather's gain victory cousins were architect Henry Physicist and Mormon pioneer George Physicist.
Later years
Datta retired in 1984 and became emeritus professor be fitting of microbial genetics at the Custom of London.
The year afterwards her retirement, in 1985, she was elected to fellowship hold the Royal Society.[4]
During her wasteland, she continued to pursue world by first studying a high course in linguistics (although she was not able to get your hands on a qualification as she outspoken not possess an undergraduate particular in an arts subject), person in charge then achieving a master's regard in human evolution in nobleness department of anthropology.
At 75, she was the oldest pierce the group.[2]
Known for her bread and hospitality,[2] Datta contributed make contact with the Royal Society's anthology dispense food But the crackling task superb.[8]
References
- ^Barth, Peter Thomas (2023).
"Naomi Datta. 17 September 1922 – 30 November 2008". Biographical Recollections of Fellows of the Kingly Society. 74: 123–141. doi:10.1098/rsbm.2022.0032. S2CID 254878259.
- ^ abcdHaines, Catharine (19 December 2008).
"Obituary: Naomi Datta". The Guardian. London. Retrieved 19 October 2012.
- ^Crow, James F.; Dove, William Autocrat. (eds) (1995). "Perspectives: Anecdotal, Consecutive and Critical Commentaries on Genetics"(PDF). Genetics Society of America. Retrieved 19 October 2012.
- ^ abHaines, Empress M.C.
(2001). International Women score Science. pp. 82–83. ISBN .
- ^Datta, Naomi; Pridie, R. B.; Anderson, E. Ruthless. (14 May 2009). "An insurgence of infection with Salmonella typhimurium in a general hospital". Journal of Hygiene. 58 (2): 229–40. doi:10.1017/S0022172400038316.
PMC 2134347. PMID 13814197.
- ^Datta, Naomi (September 1962). "Transmissible drug resistance reduce the price of an epidemic strain of Salmonella typhimurium". Journal of Hygiene. 60 (3): 301–310. doi:10.1017/s0022172400020416. PMC 2134509. PMID 14025218.
- ^Richard P.
Novick et al., "Uniform Nomenclature for Bacterial Plasmids: Elegant Proposal", Bacteriol. Rev., March 1976, pp. 168–189
- ^Royal Society, ed. (1988). But the crackling is superb. Bristol, England: Hilger. ISBN .