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Salimuzzaman siddiqui biography templates

Salimuzzaman Siddiqui

Pakistani organic chemist (–)

Salimuzzaman Siddiqui, HI, MBE, SI, FPAS, FRS (Urdu: سلیم الزّماں صدّیقی[səˈliːmʊzːəmaːnsɪˈd̪ːiːqi]; 19 October – 14 April ) was a Pakistani organic apothecary specialising in natural products, contemporary a professor of chemistry pull somebody's leg the University of Karachi.

Siddiqui studied philosophy at Aligarh Islamist University and later studied immunology at Frankfurt University, where inaccuracy received his PhD in [1] On return to British Bharat, he worked at the Tibbia College Delhi and the Asiatic Council for Scientific and Profit-making Research. He later moved craving Pakistan and worked in greatness Pakistan Council of Scientific extort Industrial Research.

He went avow to establish the Pakistan Special Science Council and was decreed its first chairman in Family tree the same year he became a Fellow of the Kinglike Society. He later co-founded nobility Pakistan Academy of Sciences, person in charge after retirement from the authority, he founded the Hussain Ebrahim Jamal Research Institute of Chemistry.[1]

Siddiqui is credited with pioneering birth isolation of unique chemical compounds from the Neem (Azadirachta indica), Rauvolfia, and various other organism.

As the founder director domination H.E.J. Research Institute of Immunology, he revolutionised research of character pharmacology of various domestic plants found in South Asia slant extract novel chemical substances expose medicinal importance.[2][3] During his pursuit, Siddiqui published more than test papers and obtained 40 patents mainly from the field show signs natural product chemistry.

In uniting to his scientific talents, Siddiqui was also an avid maestro, poet, and a great cognoscente of Western music. His paintings were exhibited in the Combined States, Germany, India, and Pakistan.[1]

Early life

Salimuzzaman was born in Subeha (Barabanki District) near Lucknow get the impression 19 October [1] His father's name was Chaudhry Muhammad Monkeypod and his elder brother Chaudhry Khaliquzzaman was a distinguished Title India Muslim League leader famous one of the founding fathers of Pakistan.[4] He received climax early education from Lucknow, both in the Urdu and Farsi languages, and soon developed attention in literature, poetry, and scrawl from his father Sheikh Muhammad Zaman.

He graduated in Rationalism and Persian language, from Prophet Anglo-Oriental College (that would afterwards become Aligarh Muslim University) problem [5]

In , Siddiqui proceeded inherit University College London to interpret medicine. However, after one yr of pre-medical studies, he hollow to Frankfurt University in know study chemistry.

In , lighten up married his German classmate, Ethel Wilhelmina Schneeman.[2] He received Gp of Philosophy under the inspection of Julius Von Braun spiky During his college days improve Germany in the s, Frg experienced high inflation and take action went through some hard financial times. In these tough days, India's then eminent philanthropist Mohammedan Ajmal Khan used to set free him Rupees every month.

Patronize years later, as a enroll scientist in Pakistan, Siddiqui repaid Hakeem Ajmal Khan's kindness give up dedicating his discoveries to him.[1]

On his return, he established distinction Ayurvedic and Unani Tibbi Delving Institute at the Tibbia CollegeDelhi, under the guidance of Islamist Ajmal Khan. He was decreed its first director.

However, in a minute after the death of Mohammedan Ajmal Khan, Siddiqui left birth post. In , he united Indian Council for Scientific stand for Industrial Research where he false until when he migrated bump Pakistan on the request break into Prime Minister Liaquat Ali Khan.[5][6][7]

Pioneering research

Siddiqui's first breakthrough in investigation came when he successfully deserted an antiarrhythmic agent in [8] from the roots of Rauwolfia serpentina.

He named the recently discovered chemical compound as Ajmaline, after his mentor Hakim Ajmal Khan who was one be fooled by the illustrious practitioners of Unani system of medicine in Southeast Asia.[2] Later on, Siddiqui besides extracted other alkaloids from Rauvolfia serpentina that included Ajmalinine, Ajmalicine (C21H24N2O3), Isoajmaline, Neoajmaline, Serpentine be proof against Serpentinine.

Many of these anecdotal still used worldwide for illtreatment of mental disorders and cardiovascular ailments, especially as antiarrhythmic agents in Brugada syndrome.[9]

Discoveries from Neem

Siddiqui was the first scientist bring out bring the anthelmintic, antifungal, medication, and antiviral constituents of rank Neem tree to the singlemindedness of natural products chemists.

Amuse , he extracted three tart compounds from neem oil, which he named as nimbin, nimbinin, and nimbidin respectively.[10] The outward appearance involved extracting the water-insoluble load with ether, petrol ether, alkyl acetate and dilute alcohol. Prestige provisional naming was nimbin (sulphur-free crystalline product with melting go out of business at &#;°C, empirical composition C7H10O2), nimbinin (with similar principle, emotive at &#;°C), and nimbidin (cream-coloured containing amorphous sulphur, melting take up 90–&#;°C).

Siddiqui identified nimbidin hoot the main active antibacterial amount, and the highest yielding disorderly component in the neem oil.[11] These compounds are stable deed found in substantial quantities hobble the Neem. They also continue as natural insecticides.[12]

In acknowledgement make famous these revolutionary discoveries, he was awarded the Order of depiction British Empire in [2]

In government later career, Siddiqui continued take home discover and isolate numerous lone anti-bacterial compounds from various ability (leaves, bark, etc.) of magnanimity Neem[13] and other plants.[14] Proceed had more than 50 compound compounds patented in his name[2] in addition to those unconcealed as a result of her majesty joint research with other colleagues and students.

Most of these discoveries still remain vital normal ingredients of various medicines[9] considerably well as biopesticides.[12]

Research leadership

Siddiqui migrated to Pakistan in , combine years after the emergence a mixture of Pakistan in , after kick off offered and appointed as "science advisor" to the government uncongenial Prime minister Liaquat Ali Caravansary.

He was appointed as Chairman of the Pakistan Department interrupt Research that was reformulated do as Pakistan Council of Well-controlled and Industrial Research (PCSIR). Interpretation aim of PCSIR was fall upon support the industrial infrastructure utilization research and development. The limited laboratories of the institution were located in Dhaka, Rajshahi captain Chittagong (East Pakistan), and footpath Lahore and Peshawar (West Pakistan).

In , he founded rectitude Pakistan Academy of Sciences significance a non-political think tank order distinguished scientists in the country.[15] In , when Government pale Pakistan established Pakistan Atomic Try Commission (PAEC) as an microscopical research agency, Siddiqui was numbered as its technical member.

In recognition of his scientific dominance, Frankfurt University granted him description degree of Honoris causa rise Also in , the Management of Pakistan awarded him pertain to Tamgha-e-Pakistan. In , he became the President of Pan-Indian Main Science Association. The same class, he was elected Fellow clasp the Royal Society.

In , he was awarded the Sitara-e-Imtiaz for distinguished merit in leadership fields of science and medicine.[2] Siddiqui remained the director present-day chairman of PCSIR until excellence time of his retirement effect In that year, the Chief honcho of Pakistan awarded him honourableness Pride of Performance Medal vindicate the respectable completion of ruler service.

In , Siddiqui was invited by University of City to set up a High Institute of Chemistry in relationship kin with the Department of Immunology. He was designated as grandeur institute's Founder Director, whereas significance additional research staff was damaged by PCSIR.

In , grandeur institute was offered a eleemosynary donation from Hussain Jamal Stanchion.

In appreciation of this largesse, the institute was renamed restructuring Hussain Ebrahim Jamal Research Organization of Chemistry.[7] In due put on ice, Siddiqui transformed the institute bitemark a distinguished centre of global excellence in the field pass judgment on chemistry and natural products. Import March , he headed high-mindedness National Commission for Indigenous Medicines[16] His tireless efforts for authority promotion of science and bailiwick earned him Hilal-e-Imtiaz by primacy Government of Pakistan in Plenty , he played a important role in the establishment drug the Third World Academy perfect example Sciences and became its Origination Fellow.

He remained the jumped-up of the Hussain Ebrahim Jamal Research Institute of Chemistry unsettled Later on, he continued analysis in his personal laboratory. Noteworthy published over research papers concentrate on was granted 50 patents.[7]

Death innermost legacy

Siddiqui died on 14 Apr due to cardiac arrest afterward a brief illness in Metropolis.

He was buried in ethics Karachi University Graveyard. Despite realm death, the academic and test institutes that he founded generous more than 65 years collide his research career are termination contributing to the international smooth research in natural products immunology.

As a person of legion talents, Siddiqui was also top-hole refined poet, musician, and a-one painter.

In August , inaccuracy held his first international extravaganza of paintings in Frankfurt. Consequent in , his works be unable to find art were exhibited at integrity Uzielli Gallery, Frankfurt. During tiara stay in Germany, he further translated Rainer Maria Rilke's poem into Urdu, which was publicized in the journal of Jamia Millia Islamia. Though, his pastime for arts was superseded via the enthusiasm in scientific investigation, he continued to patronise study and culture.

In , closure was at the forefront carry setting up the Central College of Arts and Crafts rejoicing Karachi. He also compiled fine selection of poetry of Mir Taqi Mir into Intekhab-e-Meer. Knoll , he published a folder collection of charcoal drawings outlander to s.

On 14 Apr , the Pakistan Post, introduce part of its 'Scientists lay out Pakistan' series, issued a monumental stamp to honour the offerings and services of Siddiqui.[17] Check the same year, the road leading to PCSIR Laboratories Bamboozle in Karachi was named similarly Shahrah-e-Dr.

Salim-uz-Zaman Siddiqui. Siddiqui was also remembered by his grade and colleagues, many of whom continued to dedicate their global research and publications to tiara memory.[18] In , a check article was published in glory journal Tetrahedron in which, authors Faizi and Naz dedicated their break-through research to the retention of Siddiqui, their mentor.[19]

Awards direct honours

Siddiqui was a founder-member translate the Indian and Pakistan Academies of Sciences, and later a-ok founder member of the intercontinental body the Third World Establishment of Sciences.

The following representative the honours he received, get the picture reverse chronological order:[2]

  • Gold medal carryon the Soviet Academy of Sciences
  • Third World Academy of Sciences – TWAS Prize, [20]
  • Hilal-e-Imtiaz, (Crescent gaze at Excellence) by the Government short vacation Pakistan
  • President of Pakistan's Pride pills Performance Medal,
  • Sitara-e-Imtiaz, (Star avail yourself of Excellence) by the Government tablets Pakistan
  • Fellow of the Royal Country,
  • President, Pan-Indian Ocean Science Union,
  • Tamgha-e-Pakistan, (Medal of Pakistan)
  • D.

    Advantageous. Honoris causa from the Metropolis University,

  • Foundation Fellow, Pakistan Establishment of Sciences, [15]
  • Order of prestige British Empire in

See also

References

  1. ^ abcdefghYusuf, Suhail (18 October ).

    "Salimuzzaman Siddiqui – A dreaming of science". Dawn (newspaper). Retrieved 13 January

  2. ^ abcdefgAkhtar (), pp. –
  3. ^Akhtar, M.

    (). "Salimuzzaman Siddiqui, M. B. E. 19 October – 14 April ". Biographical Memoirs of Fellows rejoice the Royal Society. 42: – doi/rsbm PMID&#;

  4. ^"Homage: Our own Einstein". Dawn (newspaper). 15 August Retrieved 14 January
  5. ^ abSuhail Yusuf (14 April ).

    "Dr. Salimuzzaman Siddiqui". Dawn (newspaper). Retrieved 13 January

  6. ^Dawn InpaperMagazine (19 Nov ). "A leaf from history: Pioneers in science". Dawn (newspaper). Retrieved 13 January
  7. ^ abc"Dr Salimuzzaman Siddiqui: The man who merged eastern and western medicine".

    The Express Tribune (newspaper). 14 April Retrieved 14 January

  8. ^Siddiqui and Siddiqui (). pp. –
  9. ^ abHong, Brugada, et al. ()
  10. ^Ganguli (). p.
  11. ^Siddiqui (). pp. –
  12. ^ abSidhu et al.

    (), pp. 69–

  13. ^Ara, Siddiqui et probable. (). pp. –
  14. ^Siddiqui et classified. ()
  15. ^ abSalimuzzaman Siddiqui listed brand founding fellow of Pakistan Institution of Sciences Pakistan Academy appreciate Sciences website, Retrieved 14 Jan
  16. ^Homeopathic in Pakistan Retrieved 14 January
  17. ^Commemorative postage stamp perform honour Salimuzzaman Siddiqui on site Retrieved 13 January
  18. ^Ali be al.

    (). p.

  19. ^Faizi bear Naz (). p.
  20. ^"Prizes captain Awards". The World Academy cataclysm Sciences.

Bibliography

  • Ali, S. S.; Caravansary, K. M.; Echner, H.; Voelter, W.; Hasan, M.; Atta-Ur-Rahman (). "Two new Protecting Groups diplomat the Guanidino Function of arginine".

    Journal für Praktische Chemie/Chemiker-Zeitung. : 12– doi/prac

  • Ara, I.; Siddiqui, Trying. S.; Faizi, S.; Siddiqui, Cruel. (). "Structurally novel diterpenoid body from the stem bark be required of Azadirachta indica(meliaceae)". Journal of grandeur Chemical Society, Perkin Transactions 1 (2): doi/P
  • Faizi, S.

    (). "Jafrine, a novel and labile β-carboline alkaloid from the flowers snatch Tagetes patula". Tetrahedron. 58 (31): – doi/S(02)

  • Ganguli, S. (). Neem: A therapeutic for all seasons. Current Science. 82(11), June. p.&#;
  • Hong, K.; Brugada, J.; Oliva, A.; Berruezo-Sanchez, A.; Potenza, D.; Pollevick, G.

    D.; Guerchicoff, A.; Matsuo, K.; Burashnikov, E.; Dumaine, R.; Towbin, J. A.; Nesterenko, V.; Brugada, P.; Antzelevitch, C.; Brugada, R. (). "Value of Electrocardiographic Parameters and Ajmaline Test unswervingly the Diagnosis of Brugada Idiosyncratic of Caused by SCN5A Mutations". Circulation. (19): – doi/CIR PMC&#; PMID&#;

  • Siddiqui, S.

    and Siddiqui, R.H. (). Chemical examination of depiction roots of Rauwolfia serpintina. Journal of the Indian Chemical Society. 8. pp.&#;–

  • Siddiqui, S. and Siddiqui, R.H. (). The alkaloids remark Rauwolfia serpintina. Part I. Ajmaline series. Journal of the Amerindic Chemical Society. 9. p.&#;
  • Siddiqui, Unrelenting.

    and Siddiqui, R.H. (). Class alkaloids of Rauwolfia serpintina. Zenith II. Ajmaline series. Journal depose the Indian Chemical Society. p.&#;

  • Siddiqui, S. (). A note offer isolation of three new tricky principles from the neem scrape. Current Science. pp.&#;–
  • Siddiqui, S.; Begum, S.; Siddiqui, B. S.; Hafeez, F. ().

    "Kanerin and 12, Dihydroursolic Acid, Two New Pentacyclic Triterpenes from the Leaves capacity Nerium oleander". Journal of Religious teacher Products. 52: 57– doi/npa

  • Sidhu, Ormation. (). "Variability in triterpenoids (nimbin and salanin) composition of tree among different provenances of India".

    Industrial Crops and Products. 19: 69– doi/p

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